Around 33,000 people get affected from Stevens Johnsons Syndrome worldwide annually. SJS causes severe blistering of the mucous membranes and skin of the body including eyes. 5% of the cases of SJS are reported to be fatal. TENS (toxic epidermal necrolysis syndrome) is a more severe variant of SJS and around 40% of TENS are reported to be fatal!
Stevens Johnson Syndrome and the Eyes
In SJS, the inside of the eyelids can get permanently damaged. This causes the edges of the eyelids to become rough while the abnormal fine lashes develop on the eyelids that rub against the cornea. SJS also results in the damage to mucous, tear and oil glands of the eye that are important in maintaining the healthy surface of the eye. The syndrome can result in extreme light sensitivity and pain, scarring and even blindness.
Currently the damage caused by SJS to the eye has no cure, however help can be provided to these patients to improve the quality of life.
PVR PROSE Treatment for Stevens-Johnson Syndrome
PVR PROSE (prosthetic replacement of the ocular surface ecosystem) can help the patients suffering with Stevens – Johnson syndrome to have their quality of life and vision restored.
PVR PROSE devices are specially designed for each individual patient and they replace or support the damaged surface of the eye to restore ocular function. This results in reduced pain and light sensitivity while improving vision.
The PVR PROSE device’s size is about the size of a nickel and is in the shape of transparent dome. They are made of plastic that’s gas permeable so that the oxygen supply to the cornea is not affected. The PVR PROSE device doesn’t rest on the cornea; instead it rests on the sclera that is relatively insensitive tissue, so that the damaged cornea gets vaulted. The cornea in return gets a healthy environment favoring its recovery and preventing any further damage to it from the environment or the eyelids.
The PVR PROSE devices are filled with saline when applying so that there’s a fluid reservoir between the cornea and the device that bathes the cornea regularly in the oxygenated artificial tears.
The patients using PVR PROSE has had a massive success with the treatment as compared to the ones using only symptomatic drugs or local lubricants and medications.